Childrens Growth and Development Research Center

Growth and development research center is one of the research centers approved by Tehran University of Medical Sciences in the children medical center since 2007 and has started activities in order to increase quality of growth and development of children in Ira n. The first activity of the center was designed to be the Registry of the metabolic diseases; in which the diseases were grouped based on the Physicians Guide to the Diagnosis, Treatment, and Follow-up of Inherited Metabolic Diseases Book.

Laboratory activities begun with setting up the MS/MS device that enabled us to investigate the Amino Acid profile and the Acyl Carnitine profile. It collaborates with pediatricians and pediatric endocrinologists, pathologists, clinical pharmacologists, medical genetics, and clinical biochemists, which the whole team is trying to diagnose and screen hereditary metabolic diseases. In fact, it is the most developed metabolic center in Iran, which collaborates with adjacent countries for metabolic screening. Inherited metabolic disorders, cell therapy and gene therapy of the inherited metabolic disorders and epidemiologic researches are among the research fields and interests of this center.

1- Screening and diagnosis of the metabolic diseases (Newborn screening)

2- Confirmation of the metabolic diseases and enzyme assay

3-genetic evaluations: NGS (Next Generation Sequencing); thus PND (Prenatal Diagnosis)

• Aghaei-Moghadam E, Mirzaaghayan MR, Zei na loo A-A, Rad EM, Zanjani KS, Alavi AH, et al. Nut ritional Status in Iranian Non-Syndromic Patients with Acyanotic Congenital Heart Disease Undergoing Su rg ical Repair. (In Press).
• Fal lahi G-H, Ahmadian JH, Rabbani A, Yousefnezhad A, Rezaei NJ Ip. Screening for cel iac disease in diabetic children from Iran. 2010;47(3):268-70.
• Moghadam EA, Mirzaaghayan MR, Ze ina loo A, Mohebbi A, Ghamari AJAoPC. Truncus arteriosus associated with double aort ic arch in a pat ient with DiGeorge syndrome: A rare case report. 2019;12(2) :185.
• Mot laghzadeh Y, Sayarifard F, Al lahverdi B, Rabbani A, Setoodeh A, Sayarifard A, et al. Assessment of vitamin D status and response to vitamin D3 in obese and non-obese Iranian children. 2016;62(4):269-75.
• Rabbani A, Alavian S-M, Motlagh ME, Ashtiani MT, Ardalan G, Salavati A, et al. Vitamin D insufficiency among children and adolescents living in Tehran, Iran. 2008;55(3) :189-91.
• Rabbani A, Mahmoudi-Gharaei J, Mohammadi MR, Motlagh ME, Mohammad K, Ardalan G, et al. Mental health problems of Iranian female adolescents and its association with pubertal development : a nationwide study. 2012:169-76.