Research Center for Rational Use of Drugs



Brief Overview 

Research Center for Rational Use of Drugs (RCRUD) was established and approved by the Council for the Development of Medical Science Universities (CDMSU) at the MOHME, Iran, in January 2011. The center has focused on conducting research projects based on real world's issues and is actively initiating collaborations with a variety of stakeholders including policy makers, insurance companies, healthcare providers, and pharmaceutical manufacturers. The main areas of research at RCRUD are Pharmcoepidemiology, Drug utilization studies, Pharmacovigilance and drug safety, Pharmaceutical Care and Patient education.




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Message from Dean 
Medicines play a vital role in the healthcare. However, challenges ahead of their safe and optimal use should be detected and overcome. The goal of the Research Center for Rational Use of Drugs (RCRUD) which is affiliated to Tehran University of Medical Sciences is to improve the safe and effective use of medicines. Our well positioned multi-disciplinary research team including clinical pharmacists, epidemiologists, physicians and health policy and public health experts tried to develop and formulate research project on different aspects of rational use of medicines and considered approaches to transfer the obtained results into practice. Any offer of assistance, partnership, or collaboration which could assist us to achieve our goal is warmly welcomed. We wish to express our sincere willingness to provide service to research centers, universities, and organizations with similar interests all around the world, specifically, countries in the region.



The mission of RCRUD is to provide highquality and reliable scientific evidence on rational use of medicines at various levels including consumers, healthcare settings and national.



  • To detect and determine research priorities to target rational use ofmedicines in national and regional level,
  • Monitoring and assessment of medicines use and its trends in the country,
  • To develop cost-effective approaches and interventions to improve rational use of medicines,
  • Conducting epidemiological and clinical studies to improve national health-care system,
  • To Provide scientific grounds for policy making and technical consultancy to policy makers and authorities in optimization of medicines use programs,
  • To encourage the partnership of the beneficiaries of rational use of medicines research including healthcare related organizations, pharmaceutical manufacturers, and international institutes,
  • To participate in education of trainees in the field of pharmacoepidemiology and Pharmacovigilance,
  • To direct and promote relevant research activities, in terms of quantity and quality,
  • To facilitate academic exchanges and collaborations at national and international levels,
  • Incorporation of research findings into clinical practice through collaborations with healthcare centers considering processes to assure safer and more effective use of medicines,
  • To provide evidence-based information about safe and effective use of medicines for clinicians, patients, policymakers and the general public.




RCRUD vision is being the preeminent source of research on pharmacoepidemiology and phramcovigilance in the country and region.
Research Fields and Interests

  • Pharmacovigilance (Adverse Drug Reaction, Medication Error)
  • Pharmcoepidemiology
  • Drug Utilization Research
  • Interventions to Improve Rational Use of Medicines
  • Pharmaceutical Care
  • Patient Education



International Collaborations
RCRUD is one of the Internat ional Network for the Rational Use of Drugs {INRUD)/lran core group members.



Degree and Non-Degree programs   Faculty Members
  • New Rout Ph.D.
  • Post-Doc Programs
  • Dean of the center: Dr. Kheirollah Gholami,  


  • Vice-Chair for Research: Dr. Maryam Taghizadeh-Ghahi, 




Faculty Members and The Scientific Council   Selected Publications
  • Dr. Seyed nasser Ostad, 


  • Dr. Arash Rashidian, 


  • Dr. Mohammadreza Javadi, 


  • Dr. Soha Namazi, 


  • Dr. Molouk Hadjibabaie, 


  • Dr. Seyed Mansour Razavi, 


  • Dr. Zahra Jahangard-Rafsanjani, 


  • Dr. Saharnaz Nedjat, 


  • Dr. Mona Kargar, 


  • Jahangard-Rafsanjani Z, Hakimzadeh N, Sarayani A, Najafi S, Heidari K, Javadi MR, Hadjibabaie M, Gholami  KH. A community pharmacy-based cardiovascular risk screening service implemented in Iran. Pharmacy Practice. 2017.15(2):919.
  • Laki B, Taghizadeh-Ghehi M, Assarian M, Heidari K, Torkamandi H, Javadi MR,, Gholami KH. Effect of hospital-wide interventions to optimize albumin use in a tertiary hospital. Journal of Clinical Pharmacy and Therapeut ics. 2017.42(6) :704-709.
  • sarayani A, Rashidian A, Gholami KH. Low utilization of diabetes medicines in Iran, despite their affordability (2000-2012): a time-series and benchmarking study. BMJ Open. 2014.
  • Mousavi S, Mansouri A, Jahangard-Rafsanjani Z, Sa rayani A, Hadjibabaie M, Gholami K. Bibliographic Search of Publication Patterns in Rational Use of Drugs in Iran: A Systematic Approach. Acta Medica lranica. 2014. 52(1): 76-81.
  • Hosseininasab M, Jahangard-Rafsanjani Z, Mohagheghi A, Sarayani A, Rashidian A, Javadi MR, Ahmadvand A, Hadjibabaie M, Gholami KH. Self-Monitoring of Blood Pressure for Improving Adherence to Antihypertensive Medicines and Blood Pressure Control: A Randomized Controlled Trial. American Journal of Hypertension. 2014.27(11):1339-45.
  • Sarayani A, Jahangard-Rafsanjani Z, Hadjibabaie M, Ahmadvand A, Javadi M, Gholami Kh. A comprehensive review of adherence to diabetes and cardiovascular medications in Iran, implications for practice and research. Journal of Diabetes and Metabolic Disorders. 2013. 12: 57. doi:l0.1186/2251-6581-12-57.



Contact Us
Address: The Fourth Floor, No. 92, Corner of South Kheradmand, - Karim Khane Zand Avenue, Hafte-Tir Square,Tehran,Iran
Tel: +982188814157
Fax: +982188814157


Last Update At : 09 February 2020