Pediatric Chronic Kidney Disease

visits: 23
About the Center

 

The Pediatric Chronic Kidney Disease (CKD) Research Center is a leading institution dedicated to advancing pediatric renal health through Real-World Evidence (RWE) and high-precision research. Leveraging a robust national registry of over 4,000 patients, the Center specializes in bridging the gap between data science and clinical practice.
Our core research excellence lies in the integration of stem cell therapy, molecular diagnostics, and Artificial Intelligence to facilitate early detection and prevent disease progression. By fostering multi-center national and international collaborations, we aim to serve as a premier global resource for evidence-based clinical guidelines and data-driven insights in pediatric nephrology.

 

Research Focus Area

 

  • Pediatric Nephrology
  • Real-World Evidence (RWE)
  • Stem Cell Therapy
  • Medical Artificial Intelligence
  • Molecular Diagnostics
  • Clinical Epidemiology
  • Precision Medicine
  • Pediatric Renal Registry Management

 

Expertise, Facilities & Research Services

 

  • National Pediatric CKD Registry (Our core strategic asset)
  • Pediatric Kidney Transplantation Research (Advancing surgical outcomes and long-term graft survival)
  • Real-World Evidence (RWE) Database
  • Clinical Trial Unit (CTU)
  • Molecular & Genetic Research Laboratory
  • Precision Medicine Analytics
  • Stem Cell Research Facility
  • Pediatric Renal Data Repository
  • Longitudinal Cohort Studies
  • Clinical Guideline Development Services
  • Multi-center Research Coordination

 

Collaboration Opportunities

 

The Pediatric Chronic Kidney Disease (CKD) Research Center actively invites national and international partners to join our mission of transforming pediatric
renal care. We seek to build high-impact collaborations ranging from joint academic research projects and multi-center clinical trials to robust industry-driven partnerships.
Leveraging our National Pediatric CKD Registry, we offer unique opportunities for Real-World Evidence (RWE) studies and longitudinal data analytics, providing a fertile ground for technology development and translational research. We welcome industry sponsors interested in advancing renal regenerative medicine, molecular diagnostics, and AI-integrated clinical tools. Furthermore, we are committed to academic excellence through visiting scholar programs, faculty exchanges, and collaborative student research. By integrating global expertise with our extensive clinical datasets, we aim to bridge the gap between innovative research and scalable clinical solutions .

Director & Key Researchers

 

Director:

  • Dr. Mastaneh Moghtaderi
  • Head of the Research Center for Pediatric Chronic Kidney Diseases in Children
  • Associate Professor of Pediatric Nephrology

Deputy Director:

  • Paniz Pourpashang
  • Research Deputy of the Research Center for Pediatric Chronic Kidney Diseases in Children
  • Assistant Professor of Pediatric Nephrology

Principal Faculty Members:

  • No principal faculty members are currently affiliated with this research center.

 

Selected Achievements

 

Article:
Age at diagnosis of undescended testis and associated factors in pediatric patients in a tertiary hospital

  • Doi: 10.1186/s12887-025-06484-w.
  • Journal: BMC pediatrics/ Cited by 1/ impact factor:2/ Q2

Urinary interleukin 13 level in steroid sensitive and resistant nephrotic syndrome: a cross-sectional single center study

  • Doi: 10.1038/s41598-025-86488-9.
  • Journal: Scientific Reports/Cited by 2/ impact factor:3.9/Q1

Systemic Comorbidities of Keloid and Hypertrophic Scars: A Phenome‑Wide Association Study in a Multiethnic U.S. Pediatric Cohort

  • Doi: https://doi.org/10.1007/s40257-026-01063-w
  • Journal: American Journal of Clinical Dermatology/Q1/ impact factor:11.4

Project:

Investigation of the efficacy of allogenic adipose tissue derived mesenchymal stem cell in children with chronic kidney disease: Phase 1 clinical trial

  • “Phase I clinical trial evaluating the safety and therapeutic potential of intravenous allogenic adipose-derived mesenchymal stem cells to delay disease progression and improve renal function in children with stage 3-4 CKD.”

Hpylori prevalence in chronic kidney disease and its relationship with gastrointestinal symptoms in reffered patient to hemodialysis ward of childrens medical center in 1390-1398 “

  • A retrospective epidemiological study investigating the prevalence of H. pylori infection and its correlation with gastrointestinal symptoms among pediatric hemodialysis patients to better understand its impact on CKD management.”

Guideline:
Adaptation of clinical practice guideline for fluid therapy in tumor lysis syndrome in pediatric patients with cancer

  • “Development and local adaptation of clinical practice guidelines for the prevention and management of Acute Tumor Lysis Syndrome to mitigate the risk of acute kidney injury in pediatric oncology patients.”
Why Collaborate with Us?

 

The Pediatric Chronic Kidney Diseases Research Center at Tehran University of Medical Sciences stands as a national reference hub, offering unique advantages for international collaboration. Our strength lies in our comprehensive national registry, currently housing over 4000 pediatric CKD patients and rapidly expanding, providing unparalleled access to real-world evidence for epidemiological and predictive studies. We boast a highly experienced faculty and a robust translational research capacity, actively developing innovative treatments through stem cell therapies and advanced molecular and AI-driven approaches for early diagnosis and management. As we aim to further internationalize our research
through multi-center projects and external funding, partnering with us offers a gateway to impactful, data-driven discoveries in pediatric nephrology.

 

Contact Information

 

  • Official name of the Center: Pediatric Chronic Kidney Diseases Research Center Tehran university of medical science
  • Postal Address: Unit 4, 2nd Floor, No. 142, West Nosrat St., Enqelab Sq., Tehran, Iran
  • Email: pckdrc@tums.ac.ir;
  • Website (if available): https://pckdrc.tums.ac.ir/
  • Google Maps location (if available): https://maps.app.goo.gl/LUVb8KGHK5Mr3sNs9
Last Update At : 07 September 2026