Research Center for Clinical Virology

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About the Center

 

The Research Center for Clinical Virology (RCCV), Tehran University of Medical Sciences (TUMS) is a multidisciplinary research center dedicated to advancing the prevention, diagnosis, surveillance, and management of viral infections through innovative clinical and molecular research. The Center brings together expertise in clinical virology, molecular epidemiology, infectious diseases, diagnostic sciences, and translational research.RCCV has a particular focus on human papillomavirus (HPV), sexually transmitted infections (STIs), HTLV-1, viral genomics, metagenomics, and microbiome research. One of its major strengths is its capacity to conduct largescale, multicenter studies and generate real-world epidemiological and molecular data. The Center has established an extensive national network of collaborating laboratories, enabling coordinated surveillance and research across multiple provinces of Iran.RCCV combines advanced molecular diagnostic capabilities with clinical and epidemiological expertise, supporting research from sample collection and laboratory diagnostics through large-scale data analysis to the translation of findings into public health strategies. Its work aims to address emerging and persistent viral health challenges, strengthen national surveillance systems, and contribute to evidence-based prevention and clinical practice. The Center's unique strength lies in integrating laboratory science, clinical research, epidemiology, and national research networks to generate high-impact evidence directly
relevant to public health.

 

Research Focus Area

 

  • Human Papillomavirus (HPV)
  • Molecular Epidemiology of Viral Infections
  • Sexually Transmitted Infections (STIs)
  • HTLV-1 Research and Surveillance
  • Viral Genomics and Molecular Diagnostics
  • Metagenomics and Microbiome Research
  • Clinical Virology
  • Infectious Disease Surveillance
  • Translational Virology
  • Public Health and Viral Infection Prevention

The Center’s research focuses on human papillomavirus (HPV), molecular epidemiology of viral infections, sexually transmitted infections (STIs), HTLV-1 research and surveillance, viral genomics, molecular diagnostics, metagenomics, microbiome research, clinical virology, and infectious disease surveillance.

 

Expertise, Facilities & Research Services

 

Molecular Virology and Advanced Molecular Diagnostics PCR-based detection, genotyping, and molecular characterization of viral pathogens. HPV Genotyping and Molecular Epidemiology – Large-scale HPV surveillance, genotype distribution, and epidemiological studies. HTLV-1 Research and Surveillance Molecular, epidemiological, and clinical investigation of HTLV-1 infection. Viral Genomics and Sequencing Genomic characterization and molecular analysis of viral pathogens. Metagenomics and Microbiome Analysis – Investigation of host-associated microbial communities and their relationship with viral infections. Large-Scale Epidemiological Studies – Design and implementation of multicenter and nationwide infectious disease studies. National Laboratory Research Network Coordination and collaboration with a nationwide network of molecular diagnostic laboratories. Biological Sample Processing and Molecular Testing – Standardized sample handling, nucleic acid extraction, PCR, and molecular testing. Bioinformatics and Research Data Analysis Management, integration, and analysis of large-scale molecular and epidemiological datasets. Translational and Collaborative Research Services – Multidisciplinary research support, protocol development, laboratory quality assessment, and collaboration with clinical, academic, and public health institutions.

Expertise, Facilities & Research Services: Molecular virology and advanced molecular diagnostics, HPV genotyping and molecular epidemiology, HTLV-1 research and surveillance, viral genomics and sequencing, metagenomics and microbiome analysis, large-scale epidemiological studies, biological sample processing and molecular testing, bioinformatics and large-scale data analysis, multicenter laboratory research networks, and translational and collaborative research.

Collaboration Opportunities

 

The Research Center for Clinical Virology (RCCV) welcomes national and international collaborations to advance research in clinical and molecular virology and to translate scientific findings into public health applications. The Center is open to joint research projects, multicenter and multinational epidemiological studies, collaborative laboratory and genomic research, clinical and translational studies, and clinical trials. We also welcome faculty and student exchanges, visiting researchers and scholars, joint training programs, and capacity-building initiatives in molecular diagnostics, viral genomics, bioinformatics, and infectious disease surveillance. RCCV is particularly interested in collaborations involving HPV, HTLV-1, sexually transmitted infections, viral genomics, metagenomics, and microbiome research. The Center also welcomes partnerships with biotechnology companies, diagnostic laboratories, pharmaceutical and healthcare organizations for technology development, validation of diagnostic tools, innovation, and research commercialization. Through its national laboratory network and multidisciplinary expertise, RCCV can facilitate large-scale collaborative studies and provide access to diverse clinical and epidemiological research settings.

 

Director & Key Researchers

 

Director: Prof. Seyed Mohammad Jazayeri, PhD – Head of the Research Center for Clinical Virology (RCCV), with expertise in clinical virology, molecular epidemiology, HPV, HBV, and viral infections. Deputy for Research: Dr. Ahmadreza Sadeghi, MD, PhD – Deputy for Research, with expertise in clinical and translational research, infectious diseases, and research development. International Affairs & Journal Executive Management: Dr. Zahra Sadeghi – Head of International Affairs and Executive Manager of Infection Prospective, the Center’s scientific journal. Key Researchers: The Center brings together a multidisciplinary team of researchers and clinicians, including Dr. Arash Letafati, Omid Salahy, Narjes Ghadiri, and Amir Aboofazeli, alongside other researchers and scientific staff with expertise in clinical virology, HPV and HTLV-1 research, molecular epidemiology, molecular diagnostics, viral genomics, epidemiology, metagenomics, microbiome research, and translational research. The Research Center for Clinical Virology (RCCV), Tehran University of Medical Sciences, is led by Prof. Seyed Mohammad Jazayeri, PhD, whose research and academic activities focus on clinical virology, molecular epidemiology, HPV, HTLV-1, and emerging and persistent viral infections. Dr. Ahmadreza Sadeghi, MD, PhD, serves as the Deputy for Research, contributing to the development and coordination of the Center’s research programs, collaborative projects, and scientific activities. Dr. Zahra Sadeghi serves as the Head of International Affairs and Executive Manager of Infection Prospective, the Center’s scientific journal, supporting international collaborations, academic communications, and the dissemination of the Center’s scientific output. The Center’s research team also includes Dr. Arash Lotfati, Omid Salahi, and Amir Aboofazeli, together with a broader multidisciplinary group of clinicians, virologists, molecular biologists, epidemiologists, laboratory scientists, and research staff. Collectively, the team brings expertise in HPV molecular epidemiology and surveillance, HTLV-1 research, sexually transmitted infections, molecular diagnostics, viral genomics, metagenomics, microbiome research, infectious disease epidemiology, bioinformatics, and translational virology. This multidisciplinary structure enables RCCV to undertake large-scale national and multicenter studies, develop collaborative research networks, and translate laboratory and epidemiological findings into clinically and publicly relevant applications.

 

Selected Achievements

 

National HPV Research and Surveillance Network: Established and coordinated a nationwide collaborative network of more than 30 molecular diagnostic laboratories across over 20 provinces, supporting large-scale HPV surveillance and epidemiological research in Iran.Large-Scale HPV Epidemiological Studies: Generated and analyzed one of the largest national datasets on HPV in Iran, including more than 100,000 referred individuals, providing comprehensive evidence on HPV prevalence, genotype distribution, age- and sex-specific patterns, and geographical variation. High- Impact Scientific Output: Produced a substantial body of peer-reviewed research in clinical and molecular virology, with major contributions to the understanding of HPV, HTLV-1, sexually transmitted infections, and viral epidemiology in Iran. Development of a National Research Infrastructure: Built multidisciplinary research capacity integrating molecular diagnostics, epidemiology, genomic approaches, bioinformatics, metagenomics, and microbiome research, enabling multicenter and translational infectious disease studies. International Scientific Engagement: Expanded international research collaborations and scientific visibility through partnerships with academic and research institutions, participation in international scientific networks and congresses, and the establishment and development of Infection Prospective as a platform for disseminating research in infectious diseases and clinical virology.

 

Why Collaborate with Us?

 

Why Collaborate with Us? The Research Center for Clinical Virology (RCCV) offers a unique combination of large-scale clinical and epidemiological datasets, an extensive national laboratory network, multidisciplinary scientific expertise, and advanced molecular research capabilities. Our extensive experience in HPV, HTLV-1, STIs, viral genomics, molecular diagnostics, metagenomics, and microbiome research enables us to design and implement large multicenter studies across Iran. RCCV provides access to diverse clinical populations and real-world laboratory data, while its integrated clinical, laboratory, epidemiological, and bioinformatics expertise supports end-to-end translational research—from molecular investigation to population-level evidence and public health impact.

 

Contact Information

 

Last Update At : 08 September 2026